Gut Microbiota and Complications of Type-2 Diabetes

The gut microbiota has been linked to the emergence of obesity, metabolic syndrome, and the onset of type 2 diabetes through decreased glucose tolerance and insulin resistance.

Uncontrolled diabetes can lead to serious health consequences such as impaired kidney function, blindness, stroke, myocardial infarction, and lower limb amputation.

Despite various treatments currently available, cases of diabetes and resulting complications are on the rise.

One promising new approach to diabetes focuses on restoring damaged gut microbiota with probiotics, prebiotics, synbiotics, and in severe cases fecal microbial transplantation.

Damage to gut microbiota composition (dysbiosis: more bad bacteria than good bacteria) has been observed in patients with type 2 diabetes and complications such as diabetic nephropathy, diabetic retinopathy, diabetic neuropathy, cerebrovascular disease, coronary heart disease, and peripheral artery disease compared to healthy controls.

The severity of gut microbiota dysbiosis was linked to disease severity, and restoring gut microbiota with probiotics in humans is linked to an improvement of symptoms and disease progression.

Repairing, regaining, and restoring gut microbiota can help with the management of type 2 diabetes and its associated complications.

The full study can be found in the December 2021 issue of Nutrients journal.

You can now get the same benefits and manage diabetes by using Projoy Probiotic.